An in vitro model system used to study adherence and invasion of Francisella tularensis live vaccine strain in nonphagocytic cells.
نویسندگان
چکیده
In observing Francisella tularensis interactions with nonphagocytic cell lines in vitro, we noted significant adherence, invasion, and intracellular growth of the bacteria within these cells. F. tularensis live vaccine strain invasion of nonprofessional phagocytic cells is inhibited by cytochalasin D and nocodazole, suggesting that both the actin and microtubule cytoskeletons are important for invasion.
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ورودعنوان ژورنال:
- Infection and immunity
دوره 75 6 شماره
صفحات -
تاریخ انتشار 2007